Dermatology Department
The Department of Dermatology is a medical specialty dedicated to the diagnosis and treatment of skin, mucous membrane, hair, nail disorders and related immune diseases. Eczema, urticaria and atopic dermatitis that you mentioned are the most common allergic or inflammatory skin diseases in dermatology, with a wide range of impacts, and they have a high incidence especially in children and people with an allergic constitution.
Department Name: Department of Dermatology (also known as Department of Dermatology and Venereology)
Core Responsibilities: Diagnosing and treating various skin diseases, sexually transmitted diseases, skin tumors, cosmetic problems (e.g., acne, pigmentation spots) and immune-related skin diseases.
Infectious skin diseases: Acne, fungal infections (tinea pedis), warts, herpes zoster
Allergic/inflammatory skin diseases: Eczema, urticaria, atopic dermatitis, contact dermatitis
Autoimmune skin diseases: Lupus erythematosus, pemphigus
Neoplastic skin diseases: Skin cancer, pigmented nevi
Hair and nail diseases: Alopecia, onychomycosis
Medical aesthetic services: Laser therapy, glycolic acid peels, injectable aesthetics
Eczema is a broad term referring to a group of chronic inflammatory skin diseases characterized by dry skin, pruritus, erythema, papules, exudation and desquamation. It can occur at any age and on any part of the body.
Acute eczema: Erythema and swelling, blisters, exudation
Subacute eczema: Erythema, crusting, desquamation
Chronic eczema: Skin thickening, roughness, hyperpigmentation
Allergens (dust mites, pollen, food)
Irritants (detergents, fragrances, metals)
Dry climate, excessive sweating
Mental stress, decreased immunity
Hands, cubital fossae, popliteal fossae, face, neck
Commonly known as hives, urticaria is a sudden, transient, severely pruritic edematous skin reaction, manifested as well-demarcated erythematous or pale wheals. The lesions usually resolve spontaneously within 24 hours but may recur repeatedly.
| Type | Characteristics |
|---|---|
| Acute Urticaria | Lasts < 6 weeks, often triggered by food, drugs or infections |
| Chronic Urticaria | Recurrent episodes for > 6 weeks; the cause is unidentified in most cases (referred to as Chronic Spontaneous Urticaria, CSU) |
Sudden pruritus → Erythematous and edematous wheals appearing on the skin
Wheals vary in size and shape, and may coalesce into plaques
Resolve spontaneously within 24 hours without leaving scars, with new lesions emerging continuously
Severe cases may be accompanied by angioedema (swelling of the eyelids, lips and throat)
Food (seafood, nuts, eggs)
Medications (antibiotics, analgesics)
Infections (viral, bacterial)
Insect bites
Physical stimuli (cold, heat, sunlight, pressure)
Autoimmune factors (common in chronic urticaria)
Atopic Dermatitis (AD) is a chronic, recurrent, pruritic and inflammatory skin disease, which is a component of the atopic diathesis. It often coexists with allergic rhinitis and asthma, and is regarded as the starting point of the Atopic March.
✅ Atopic Diathesis: A genetic predisposition that makes an individual susceptible to allergic diseases.
Chronic pruritus
Typical skin lesions and distribution patterns
Personal or family history of allergies (e.g., asthma, rhinitis)个人或家族过敏史(如哮喘、鼻炎)
| Age Group | Predominantly Affected Areas | Clinical Features |
|---|---|---|
| Infant stage (0–2 years) | Face, scalp, extensor aspects of limbs | Erythema, exudation, crusting |
| Childhood stage (2–12 years) | Cubital fossae, popliteal fossae, wrists, ankles | Skin thickening, lichenification |
| Adolescent and adult stage | Neck, eyelids, hands, trunk | Chronic eczematous changes, severe pruritus |
Impaired skin barrier function (e.g., filaggrin gene mutation)
Excessive immune system response
Microbial dysbiosis (e.g., Staphylococcus aureus colonization)
| Item | Eczema | Urticaria | Atopic Dermatitis |
|---|---|---|---|
| Course of Disease | Chronic, recurrent | Acute/chronic, wheals appear and resolve rapidly | Chronic, onset in infancy |
| Skin Lesion Characteristics | Erythema, papules, exudation, desquamation | Wheals (mosquito-bite-like), resolving within 24 hours | Lichenification, symmetric distribution |
| Pruritus | Obvious | Severe | Severe intractable pruritus |
| Duration | Several days to weeks | Individual wheals < 24 hours | Persistent long-term |
| Association with Allergy | May be associated | Common trigger factor | Strongly associated, often complicated with asthma/rhinitis |
| Family History | May be present | Rare | Often with a family history of allergy |
? Simple Mnemonics:
Urticaria:Onset fast, resolution fast, intense itching
Eczema: Recurrent rashes, dry skin, easy to break
Atopic Dermatitis: Onset in early childhood, itching severe enough to disrupt sleep, family history of allergies
Daily moisturization: Use fragrance-free, non-irritating moisturizers (e.g., Vaseline, CeraVe, Aveeno)
Gentle cleansing: Avoid hot water scrubbing, minimize soap use
Avoid scratching: Keep nails short and wear cotton clothing
| Disease | Main Medications |
|---|---|
| Eczema / Atopic Dermatitis | - Topical glucocorticoids (e.g., hydrocortisone butyrate) - Topical calcineurin inhibitors (e.g., tacrolimus) - Oral antihistamines (for pruritus relief) - Oral immunosuppressants or biologics (e.g., dupilumab) for severe cases |
| Urticaria | - Oral antihistamines (loratadine, cetirizine) - Dose escalation or combination therapy for chronic cases - Glucocorticoids or biologics (omalizumab) for severe cases |
Undergo allergen testing (IgE testing, skin prick testing)
Keep a food diary (if food allergy is suspected)
Avoid contact with known allergens
Dupilumab (Dupixent): Indicated for atopic dermatitis and asthma, exerts a significant effect by targeted inhibition of inflammatory pathways.
Omalizumab: Indicated for chronic urticaria and allergic asthma.
Seek medical attention promptly if you or a family member experience the following conditions:
Recurrent skin pruritus and rashes that disrupt sleep
Erythema and exudation on an infant’s face with suspected atopic dermatitis
Sudden onset of wheals with recurrent episodes for more than 6 weeks
Refractory eczema with skin thickening and fissures
The need for definitive allergen identification and standardized treatment
| Disease | Key Features | Treatment Focus |
|---|---|---|
| Eczema | Chronic pruritus, dry skin | Moisturization + topical glucocorticoids |
| Urticaria | Wheals, sudden onset and rapid resolution | Antihistamines + trigger identification |
| Atopic Dermatitis | Onset in infancy, family history of allergy | Barrier repair + anti-inflammatory therapy |
? Warm Reminder:
Do not use potent glucocorticoid ointments for a long time without medical supervision; their use must be under the guidance of a doctor.
Eczema is not caused by "moisture", but by impaired skin barrier function — the drier the skin, the more likely an outbreak is to occur.
Atopic dermatitis is the starting point of the "atopic march"; early intervention can reduce the risk of developing asthma and rhinitis in the future.
If you experience related symptoms, it is recommended to consult a dermatologist or allergologist as early as possible. With scientific management, you can bid farewell to the distress of pruritus!
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